Limited joint mobility in diabetes

The interaction between hyperglycemia and connective tissue problems explained

Several rheumatologic manifestations are more pronounced in subjects with diabetes, ie, frozen shoulder, rotator cuff tears, Dupuytren’s contracture, trigger finger, cheiroarthropathy in the upper limb, and Achilles tendinopathy and plantar fasciitis in the lower limb. Limited ROM is often significantly affecting ADL, leading to further complications like diabetic foot ulcers and is very difficult to manage or reduce once established.

The most extensive accumulation of AGEs occurs in tissues with low turnover, such as cartilage, bone, and tendon.

This review provides a short description of diabetes-related joint diseases, the specific pathogenetic mechanisms involved, and the role of inflammation, overuse, and genetics, each of which activates a complex sequence of biochemical alterations.


Curious about the rest of the article?

Sign up as a member of the Anatomy & Physiotherapy Society. 
Check out the benefits of a membership and give it a try today! 
Or have a look at our monthly featured article (free) on our homepage.

Already a member? Login here below

Signup for our weekly or monthly newsletter and get notified on updates on the themes you're interested in:

Please enable the javascript to submit this form

Anatomy & Physiotherapy is a joint venture
between SoPhy & Sharing Science

Summaries on Physiotherapy B.V.
Berkenweg 7
Postbus 1161
3800 BD Amersfoort
The Netherlands

Chamber of commerce: 74973738
Bank: NL72ABNA0849809959
V.A.T. number: NL860093530B01

Sharing Science
Rijksweg Zuid 99
6134 AA Sittard
The Netherlands
Chamber of Commerce: 58306862